Table of Contents
Cover
Title Page
Copyright
Preface
Acknowledgments
Abbreviations
Chapter 1: Introduction: The Origin, Current Status, and Future of Microfluidics
1.1 Introduction
1.2 Development of Microfluidic Components
1.3 Development of Complex Microfluidic Systems
1.4 Development of Application-Oriented Microfluidic Systems
1.5 Perspective
References
Chapter 2: Fundamental Concepts and Physics in Microfluidics
2.1 Introduction
2.2 Basic Concepts of Liquids and Gases
2.3 Mass and Heat Transfer Principles for Fluid
2.4 Surfaces and Interfaces in Microfluidics
2.5 Development of Driving Forces for Microfluidic Processes
2.6 Construction Materials Considerations
Acknowledgments
References
Chapter 3: Microfluidics Devices: Fabrication and Surface Modification
3.1 Introduction
3.2 Microfluidics Device Fabrication
3.3 Surface Modification in Microfluidics Fabrication
3.4 Conclusions and Outlook
References
Chapter 4: Numerical Simulation in Microfluidics and the Introduction of the Related Software
4.1 Introduction
4.2 Numerical Simulation Models in Microfluidics
4.3 Numerical Simulation Software in Microfluidics
4.4 Conclusions
Acknowledgments
References
Chapter 5: Digital Microfluidic Systems: Fundamentals, Configurations, Techniques, and Applications
5.1 Introduction to Microfluidic Systems
5.2 Types of Digital Microfluidic Systems
5.3 DMF Chip Fabrication Techniques
5.4 Different Electrode Configurations in DMF Systems
5.5 Digital Microfluidic Working Principle
5.6 Electrical Signals Used and Their Effect on the DMF Operations
5.7 Droplet Metering and Dispensing Techniques in DMF Systems
5.8 The Effect of the Gap Height between the Top Plate and the Bottom Plate in DMF Systems
5.9 Modeling and Controlling Droplet Operations in DMF Systems
5.10 Prospects of Portability in DMF Platforms
5.11 Examples for Chemical and Biological Applications Performed on the DMF Platform
References
Chapter 6: Microfluidics for Chemical Analysis
6.1 Introduction
6.2 Microfluidics for Electrochemical Analysis
6.3 Advanced Microfluidic Methodologies for Electrochemical Analysis
6.4 Numerical Modeling of Electrochemical Microfluidic Technologies
References
Chapter 7: Microfluidic Devices for the Isolation of Circulating Tumor Cells (CTCs)
7.1 Introduction
7.2 Affinity-Based Enrichment of CTCs
7.3 Nonaffinity-Based Enrichment of CTCs
7.4 Conclusions and Outlook
References
Chapter 8: Microfluidics for Disease Diagnosis
8.1 Introduction
8.2 Protein Analysis
8.3 Nucleic Acid Analysis
8.4 Cell Detection
8.5 Other Species
8.6 Summary and Overlook
References
Chapter 9: Gene Expression Analysis on Microfluidic Device
9.1 Introduction
9.2 Analysis Cell Population Gene Expression on Chip
9.3 Single-Cell Gene Expression Profiling
9.4 Conclusion
Acknowledgment
References
Chapter 10: Computational Microfluidics Applied to Drug Delivery in Pulmonary and Arterial Systems
10.1 Introduction
10.2 Modeling Methods
10.3 Pulmonary Drug Delivery
10.4 Intravascular Drug Delivery
10.5 Conclusions and Future Work
References
Chapter 11: Microfluidic Synthesis of Organics
11.1 Introduction
11.2 Microfluidic Nebulator for Organic Synthesis
11.3 Coiled Tubing Microreactor for Organic Synthesis
11.4 Chip-Based Microfluidic Reactor for Organic Synthesis
11.5 Packed-Bed Microreactors for Organic Synthesis
11.6 Ring-Shaped (Tube-in-Tube) Microfluidic Reactor for Organic Synthesis
11.7 Summary and Outlook
Acknowledgments
References
Chapter 12: Microfluidic Approaches for Designing Multifunctional Polymeric Microparticles from Simple Emulsions to Complex Particles
12.1 Introduction
12.2 Flow Regimes in Microfluidics: Dripping, Jetting, and Coflowing
12.3 Design of Multifunctional Microparticles from Emulsions
12.4 Conclusions and Outlooks
References
Chapter 13: Synthesis of Magnetic Nanomaterials
13.1 Introduction
13.2 Synthesis of Magnetic Nanomaterials Using Microreactors
13.3 Conclusion
References
Chapter 14: Microfluidic Synthesis of Metallic Nanomaterials
14.1 Introduction
14.2 Microfluidic Processes for Metallic Nanomaterial Synthesis
14.3 Crystal Structure-Controlled Synthesis of Metallic Nanocrystals
14.4 Size- and Shape-Controlled Synthesis of Metallic Nanocrystals
14.5 Multi-Hierarchical Microstructure- and Composition-Controlled Synthesis of Metallic Nanocrystals
14.6 Summary and Outlook
Acknowledgments
References
Chapter 15: Microfluidic Synthesis of Composites
15.1 Introduction
15.2 Microfluidic Synthesis Systems and the Design Principles
15.3 The Formation Mechanism of Composites
15.4 Microfluidic Synthesis of Composites
15.5 Summary and Perspectives
Acknowledgments
References
Chapter 16: Microfluidic Synthesis of MOFs and MOF-Based Membranes
16.1 Microfluidic Synthesis of Metal–Organic Frameworks (MOFs)
16.2 Microfluidic Synthesis of MOF-Based Membranes
16.3 Conclusions and Outlook
Acknowledgments
References
Chapter 17: Perspective for Microfluidics
17.1 Design, Fabrication, and Assemble of Microfluidic Systems
17.2 Precise Control of Critical Device Features for Chemical Analysis and Biomedical Engineering
17.3 Control of Critical Kinetic Parameters for Chemical and Materials Synthesis
17.4 Development of Fundamental Theory at Micro-/Nanoscale and Fluid Mechanism at Nanoliter–Picoliter for Microfluidic Systems
Acknowledgments
References
Index
End User License Agreement
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Guide
Cover
Table of Contents
Preface
Begin Reading